Expected and Unexpected Features of the Newly Discovered Bat Influenza A-like Viruses

نویسندگان

  • Wenjun Ma
  • Adolfo García-Sastre
  • Martin Schwemmle
  • Rebecca Ellis Dutch
چکیده

1 Department of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, Kansas, United States of America, 2 Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, 3 Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, 4 Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, 5 Institute of Virology, University Medical Center Freiburg, Freiburg, Germany

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Unexpected Functional Divergence of Bat Influenza Virus NS1 Proteins

Recently, two influenza A virus (FLUAV) genomes were identified in Central and South American bats. These sequences exhibit notable divergence from classical FLUAV counterparts, and functionally, bat FLUAV glycoproteins lack canonical receptor binding and destroying activity. Nevertheless, other features that distinguish these viruses from classical FLUAVs have yet to be explored. Here, we stud...

متن کامل

Unusual Influenza A Viruses in Bats

Influenza A viruses infect a remarkably diverse number of hosts. Two completely new influenza A virus subtypes were recently discovered in bats, dramatically expanding the host range of the virus. These bat viruses are extremely divergent from all other known strains and likely have unique replication cycles. Phylogenetic analysis indicates long-term, isolated evolution in bats. This is support...

متن کامل

Investigation of a Potential Zoonotic Transmission of Orthoreovirus Associated with Acute Influenza-Like Illness in an Adult Patient

Bats are increasingly being recognized as important reservoir hosts for a large number of viruses, some of them can be highly virulent when they infect human and livestock animals. Among the new bat zoonotic viruses discovered in recent years, several reoviruses (respiratory enteric orphan viruses) were found to be able to cause acute respiratory infections in humans, which included Melaka and ...

متن کامل

Prevalence of Respiratory Syncytial Virus, Adenovirus and Rhinovirus in Patients with flu-like symptoms Admitted to Mazandaran Province Health Centers in north of Iran – a cross–sectional study

Background: The main viral causes of acute respiratory diseases (ARDs) include influenza viruses A and B, respiratory syncytial virus (RSV), adenovirus (ADV), rhinovirus, and parainfluenza viruses (PIV). This study aimed to investigate the prevalence of respiratory RSV, ADV and rhinovirus in patients with flu-like symptoms admitted to Mazandaran province health centers in north of Iran. Metho...

متن کامل

Synthetically derived bat influenza A-like viruses reveal a cell type- but not species-specific tropism.

Two novel influenza A-like viral genome sequences have recently been identified in Central and South American fruit bats and provisionally designated "HL17NL10" and "HL18NL11." All efforts to isolate infectious virus from bats or to generate these viruses by reverse genetics have failed to date. Recombinant vesicular stomatitis virus (VSV) encoding the hemagglutinin-like envelope glycoproteins ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 11  شماره 

صفحات  -

تاریخ انتشار 2015